Version 5.4
Mus musculus Protein: Stard10
Summary
InnateDB Protein IDBP-625671.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stard10
Protein Name START domain containing 10
Synonyms AV048538; CGI-52; NY-C0-28; PC-TP2; PCTP2; Pctpl; Sdccag28; SdccagG28; TISP-81;
Species Mus musculus
Ensembl Protein ENSMUSP00000133002
InnateDB Gene IDBG-201884 (Stard10)
Protein Structure
UniProt Annotation
Function Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes (By similarity). May play metabolic roles in sperm maturation or fertilization. {ECO:0000250, ECO:0000269PubMed:10819773}.
Subcellular Localization Cell projection, cilium, flagellum {ECO:0000269PubMed:10819773}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Mainly cytosolic (By similarity). In testis was predominantly detected at the flagella of elongated spermatids, with a strong signal also found at the tail of epididymal sperm. {ECO:0000250}.
Disease Associations
Tissue Specificity Testis, kidney, liver, and intestine with the highest level in the testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0032782 bile acid secretion
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway
Cellular Component
GO:0005829 cytosol
GO:0005902 microvillus
GO:0005929 cilium
GO:0016020 membrane
GO:0046581 intercellular canaliculus
Protein Structure and Domains
PDB ID MGI:1860093
InterPro IPR002913 START domain
PFAM PF01852
PRINTS
PIRSF
SMART SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JMD3
PhosphoSite PhosphoSite-Q9JMD3
TrEMBL Q0VG22
UniProt Splice Variant
Entrez Gene 56018
UniGene Mm.28896
RefSeq
MGI ID
MGI Symbol Stard10
OMIM
CCDS CCDS21509
HPRD
IMGT
EMBL AB031550 AC107638 AC129079 BC116984 BC120641 CH466531
GenPept AAI16985 AAI20642 BAA92233 EDL16502 EDL16506

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca