InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arsa

Summary

InnateDB Protein

IDBP-625835.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arsa

Protein Name

arylsulfatase A

Synonyms

As-2; AS-A; As2; ASA; AW212749; TISP73;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127646

InnateDB Gene

IDBG-174392 (Arsa)

Protein Structure

UniProt Annotation

Function

Hydrolyzes cerebroside sulfate.

Subcellular Localization

Lysosome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004065	arylsulfatase activity
GO:0004098	cerebroside-sulfatase activity
GO:0005509	calcium ion binding
GO:0008484	sulfuric ester hydrolase activity

Biological Process

GO:0006914	autophagy
GO:0007339	binding of sperm to zona pellucida
GO:0007417	central nervous system development
GO:0007584	response to nutrient
GO:0008152	metabolic process
GO:0009268	response to pH
GO:0043627	response to estrogen
GO:0045471	response to ethanol
GO:0051597	response to methylmercury

Cellular Component

GO:0001669	acrosomal vesicle
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005768	endosome
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0031232	extrinsic component of external side of plasma membrane
GO:0070062	extracellular vesicular exosome