InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lgr5

Summary

InnateDB Protein

IDBP-626497.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lgr5

Protein Name

leucine rich repeat containing G protein coupled receptor 5

Synonyms

FEX; Gpr49;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133707

InnateDB Gene

IDBG-190951 (Lgr5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	0
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0016500	protein-hormone receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0048839	inner ear development

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1341817

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR002131 Glycoprotein hormone receptor family
IPR003591 Leucine-rich repeat, typical subtype
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001
PF01462
PF00560
PF13504
PF13855

PRINTS

PR00237
PR00373

PIRSF

SMART

SM00013
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UXI8

UniProt Splice Variant

Entrez Gene

14160

UniGene

Mm.42103

RefSeq

MGI ID

MGI Symbol

Lgr5

OMIM

CCDS

HPRD

IMGT

EMBL

AC126943 AC129329

GenPept