InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Upp1

Summary

InnateDB Protein

IDBP-626742.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Upp1

Protein Name

uridine phosphorylase 1

Synonyms

AI325217; UdRPase; Up; UPase; Upp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127473

InnateDB Gene

IDBG-149661 (Upp1)

Protein Structure

UniProt Annotation

Function

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004850	uridine phosphorylase activity

Biological Process

GO:0006220	pyrimidine nucleotide metabolic process
GO:0009116	nucleoside metabolic process
GO:0009166	nucleotide catabolic process
GO:0042149	cellular response to glucose starvation
GO:0044206	UMP salvage
GO:0046108	uridine metabolic process