Version 5.4
| Mus musculus Protein: Galnt5 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-627007.2 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Galnt5 | ||||||
| Protein Name | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000131362 | ||||||
| InnateDB Gene | IDBG-171811 (Galnt5) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity). {ECO:0000250}. | ||||||
| Subcellular Localization | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Expressed at low level. Not expressed before E7.5 during embryogenesis. Expressed in dental mesenchyme and tongue. Accumulates in a subset of mesenchymal cells at the ventral-most portions of the E12.5 maxilla and mandible underlying the dental lamina. {ECO:0000269PubMed:11159923}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:2179403 | ||||||
| InterPro |
IPR000772
Ricin B lectin domain IPR001173 Glycosyltransferase 2-like IPR029044 Nucleotide-diphospho-sugar transferases |
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| PFAM |
PF00652
PF14200 PF00535 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00458
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q8C102 | ||||||
| PhosphoSite | PhosphoSite-Q8C102 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 241391 | ||||||
| UniGene | Mm.68639 | ||||||
| RefSeq | XP_006498111 | ||||||
| MGI ID | |||||||
| MGI Symbol | Galnt5 | ||||||
| OMIM | |||||||
| CCDS | CCDS38125 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK029323 AL928564 AL929144 CH466519 | ||||||
| GenPept | BAC26396 CAM18783 CAM24473 EDL26932 | ||||||