InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Idi1

Summary

InnateDB Protein

IDBP-627224.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Idi1

Protein Name

isopentenyl-diphosphate delta isomerase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000132780

InnateDB Gene

IDBG-129163 (Idi1)

Protein Structure

UniProt Annotation

Function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). {ECO:0000250}.

Subcellular Localization

Peroxisome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004452	isopentenyl-diphosphate delta-isomerase activity
GO:0016787	hydrolase activity
GO:0030145	manganese ion binding

Biological Process

GO:0006695	cholesterol biosynthetic process
GO:0008299	isoprenoid biosynthetic process
GO:0035634	response to stilbenoid
GO:0045087	innate immune response (InnateDB)
GO:0050992	dimethylallyl diphosphate biosynthetic process