InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Brsk2

Summary

InnateDB Protein

IDBP-627292.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Brsk2

Protein Name

BR serine/threonine kinase 2

Synonyms

4833424K13Rik; SAD-A; SADA;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000134170

InnateDB Gene

IDBG-212422 (Brsk2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0030010	establishment of cell polarity
GO:0030182	neuron differentiation
GO:0048812	neuron projection morphogenesis

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1923020

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UYP7

UniProt Splice Variant

Entrez Gene

75770

UniGene

Mm.482784

RefSeq

MGI ID

MGI Symbol

Brsk2

OMIM

CCDS

HPRD

IMGT

EMBL

AL603836 AL772165

GenPept