InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rasgef1a

Summary

InnateDB Protein

IDBP-627339.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rasgef1a

Protein Name

RasGEF domain family, member 1A

Synonyms

6330404M18Rik; AI835194;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000132244

InnateDB Gene

IDBG-181285 (Rasgef1a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005088	Ras guanyl-nucleotide exchange factor activity

Biological Process

GO:0007264	small GTPase mediated signal transduction
GO:0016477	cell migration
GO:0032318	regulation of Ras GTPase activity
GO:0032320	positive regulation of Ras GTPase activity
GO:0046579	positive regulation of Ras protein signal transduction
GO:0051056	regulation of small GTPase mediated signal transduction

Cellular Component

GO:0005575	cellular_component
GO:0005622	intracellular

Protein Structure and Domains

PDB ID

MGI:1917977

InterPro

IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
IPR001895 Guanine-nucleotide dissociation stimulator CDC25
IPR023578 Ras guanine nucleotide exchange factor, domain

PFAM

PF00618
PF00617

PRINTS

PIRSF

SMART

SM00229
SM00147

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite