InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mpp6

Summary

InnateDB Protein

IDBP-627542.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mpp6

Protein Name

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

Synonyms

P55t; Pals2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125880

InnateDB Gene

IDBG-146671 (Mpp6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane; Peripheral membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004385	guanylate kinase activity
GO:0005515	protein binding
GO:0030165	PDZ domain binding

Biological Process

GO:0046939

nucleotide phosphorylation

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1927340

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR004172 L27
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR014775 L27, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM