Version 5.4
Mus musculus Protein: Slc43a2
Summary
InnateDB Protein IDBP-627921.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc43a2
Protein Name solute carrier family 43, member 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000126838
InnateDB Gene IDBG-200164 (Slc43a2)
Protein Structure
UniProt Annotation
Function Sodium-, chloride-, and pH-independent, high affinity transport of large neutral amino acids. {ECO:0000269PubMed:15659399}.
Subcellular Localization Membrane {ECO:0000269PubMed:15659399}; Multi-pass membrane protein {ECO:0000269PubMed:15659399}.
Disease Associations
Tissue Specificity Expressed in intestine, kidney, brain and adipose tissue, heart and testis. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus. {ECO:0000269PubMed:15659399}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015179 L-amino acid transmembrane transporter activity
Biological Process
GO:0015807 L-amino acid transport
GO:0055085 transmembrane transport
GO:1902475 L-alpha-amino acid transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2442746
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CGA3
PhosphoSite PhosphoSite-Q8CGA3
TrEMBL Q5ND25
UniProt Splice Variant
Entrez Gene 215113
UniGene Mm.487399
RefSeq NP_001186212
MGI ID
MGI Symbol Slc43a2
OMIM
CCDS CCDS25051
HPRD
IMGT
EMBL AB120363 AK143773 AK159144 AL591440 AL591496 BC042513 BK005643
GenPept AAH42513 BAD91090 BAE25533 BAE34852 CAI24094 CAI35390 DAA05677

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca