Version 5.4
Homo sapiens Protein: PRTFDC1
Summary
InnateDB Protein IDBP-63205.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRTFDC1
Protein Name phosphoribosyl transferase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000365556
InnateDB Gene IDBG-63195 (PRTFDC1)
Protein Structure
UniProt Annotation
Function Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0042803 protein homodimerization activity
Biological Process
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR029057 Phosphoribosyltransferase-like
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NRG1
PhosphoSite PhosphoSite-Q9NRG1
TrEMBL
UniProt Splice Variant
Entrez Gene 56952
UniGene Hs.604693
RefSeq
HUGO HGNC:23333
OMIM 610751
CCDS
HPRD 17917
IMGT
EMBL AB209792 AF226056 AK021950 AK222674 AK294130 AL157385 AL512598 BC008662 CH471072
GenPept AAF86956 AAH08662 BAB13944 BAD93029 BAD96394 BAH11679 CAH70349 CAH70350 CAH70351 CAH70785 CAH70786 CAH70787 EAW86120

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca