InnateDB Protein
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IDBP-63466.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RILPL2
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Protein Name
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Rab interacting lysosomal protein-like 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000280571
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InnateDB Gene
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IDBG-63464 (RILPL2)
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Protein Structure
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Function |
Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport, including protein transport away from primary cilia. May function via activation of RAC1 and PAK1 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytosol {ECO:0000269PubMed:14668488}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell projection, cilium {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. Expressed at higher level in lung. {ECO:0000269PubMed:14668488}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0042802
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identical protein binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR021563
Rab interacting lysosomal protein
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PFAM |
PF11461
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q969X0
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PhosphoSite |
PhosphoSite-Q969X0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
196383
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UniGene |
Hs.605175
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RefSeq |
NP_659495
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HUGO |
HGNC:28787
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OMIM |
614093
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CCDS |
CCDS9248
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HPRD |
10084
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IMGT |
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EMBL |
AB085763
AK056934
BC013042
CH471054
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GenPept |
AAH13042
BAB71313
BAC76826
EAW98411
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