InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ACBD5

Summary

InnateDB Protein

IDBP-64803.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACBD5

Protein Name

acyl-CoA binding domain containing 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000365070

InnateDB Gene

IDBG-64801 (ACBD5)

Protein Structure

UniProt Annotation

Function

Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters. {ECO:0000269PubMed:24535825}.

Subcellular Localization

Peroxisome membrane {ECO:0000250}; Single- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000062	fatty-acyl-CoA binding
GO:0003674	molecular_function
GO:0008289	lipid binding

Biological Process

GO:0006810	transport
GO:0008150	biological_process
GO:0030242	peroxisome degradation

Cellular Component

GO:0005634	nucleus
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle