Version 5.4
Homo sapiens Protein: GLIPR2
Summary
InnateDB Protein IDBP-64826.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLIPR2
Protein Name GLI pathogenesis-related 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367196
InnateDB Gene IDBG-64824 (GLIPR2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:11865038}; Lipid-anchor {ECO:0000269PubMed:11865038}. Note=Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.
Disease Associations
Tissue Specificity Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney. {ECO:0000269PubMed:12137952}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0042803 protein homodimerization activity
Biological Process
GO:0010634 positive regulation of epithelial cell migration
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0000139 Golgi membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001283 Cysteine-rich secretory protein, allergen V5/Tpx-1-related
IPR014044 CAP domain
PFAM PF00188
PRINTS PR00837
PIRSF PIRSF038921
SMART SM00198
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H4G4
PhosphoSite PhosphoSite-Q9H4G4
TrEMBL D3DRP5
UniProt Splice Variant
Entrez Gene 152007
UniGene Hs.621690
RefSeq NP_071738
HUGO HGNC:18007
OMIM 607141
CCDS CCDS6598
HPRD 06187
IMGT
EMBL AJ011129 AK074488 AK075091 AL158830 AY039756 BC017918 CH471071
GenPept AAH17918 AAK83460 BAC11019 BAC11395 CAC12812 CAH73678 EAW58315 EAW58316

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca