InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EDAR

Summary

InnateDB Protein

IDBP-65180.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EDAR

Protein Name

ectodysplasin A receptor

Synonyms

DL; ECTD10A; ECTD10B; ED1R; ED3; ED5; EDA-A1R; EDA1R; EDA3; HRM1;

Species

Homo sapiens

Ensembl Protein

ENSP00000365839

InnateDB Gene

IDBG-65178 (EDAR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding

Biological Process

GO:0006915	apoptotic process
GO:0007165	signal transduction
GO:0008544	epidermis development
GO:0030154	cell differentiation

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000488 Death domain
IPR011029 Death-like domain

PFAM

PF00531

PRINTS

PIRSF

SMART

SM00005

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UNE0

PhosphoSite

PhosphoSite-Q9UNE0

TrEMBL

UniProt Splice Variant

Entrez Gene

10913

UniGene

Hs.171971

RefSeq

XP_006712267

HUGO

HGNC:2895

OMIM

604095

CCDS

HPRD

04974

IMGT

EMBL

AC073415 AC092160 AC133784 AF130988 AF130990 AF130991 AF130992 AF130993 AF130994 AF130995 AF130996 AK296936 AK313781 BC093870 BC093872 CH471182

GenPept

AAD50076 AAD50077 AAH93870 AAH93872 BAG36519 BAG59487 EAW53869