InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNF140

Summary

InnateDB Protein

IDBP-66230.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNF140

Protein Name

zinc finger protein 140

Synonyms

pHZ-39;

Species

Homo sapiens

Ensembl Protein

ENSP00000347755

InnateDB Gene

IDBG-66228 (ZNF140)

Protein Structure

UniProt Annotation

Function

May be involved in transcriptional regulation as a repressor.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like

PFAM

PF01352
PF00096

PRINTS

PIRSF

SMART

SM00349
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P52738

PhosphoSite

PhosphoSite-P52738

TrEMBL

Q05CP6

UniProt Splice Variant

Entrez Gene

7699

UniGene

Hs.606528

RefSeq

NP_003431

HUGO

HGNC:12925

OMIM

604082

CCDS

CCDS9282

HPRD

04966

IMGT

EMBL

AC026786 AC073911 AK122741 AK296572 AK303240 BC022291 BC040561 CH471218 U09368

GenPept

AAC50262 AAH22291 AAH40561 BAG53698 BAG59192 BAG64326 EAW54795 EAW54797 EAW54798