Version 5.4
Homo sapiens Protein: HAS1
Summary
InnateDB Protein IDBP-66245.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAS1
Protein Name hyaluronan synthase 1
Synonyms HAS;
Species Homo sapiens
Ensembl Protein ENSP00000222115
InnateDB Gene IDBG-66243 (HAS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0050501 hyaluronan synthase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006024 glycosaminoglycan biosynthetic process
GO:0007155 cell adhesion
GO:0010764 negative regulation of fibroblast migration
GO:0030203 glycosaminoglycan metabolic process
GO:0030212 hyaluronan metabolic process
GO:0030213 hyaluronan biosynthetic process
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0044281 small molecule metabolic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0085029 extracellular matrix assembly
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001173 Glycosyltransferase 2-like
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00535
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92839
PhosphoSite PhosphoSite-Q92839
TrEMBL Q4VHE4
UniProt Splice Variant
Entrez Gene 3036
UniGene Hs.57697
RefSeq NP_001514
HUGO HGNC:4818
OMIM 601463
CCDS CCDS12838
HPRD 03271
IMGT
EMBL AC018755 AY916556 CH471135 D84424 U59269
GenPept AAC50706 AAF87845 AAY52132 BAA12351 EAW72038

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca