Version 5.4
Homo sapiens Protein: ABCF3
Summary
InnateDB Protein IDBP-67579.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCF3
Protein Name ATP-binding cassette, sub-family F (GCN20), member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000292808
InnateDB Gene IDBG-67577 (ABCF3)
Protein Structure
UniProt Annotation
Function Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0051607 defense response to virus
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00005
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NUQ8
PhosphoSite PhosphoSite-Q9NUQ8
TrEMBL
UniProt Splice Variant
Entrez Gene 55324
UniGene Hs.361323
RefSeq
HUGO HGNC:72
OMIM
CCDS
HPRD 12404
IMGT
EMBL AK002060 AK024758 AK092415 AK290106 BC009253 BC051754 BC051884
GenPept AAH09253 AAH51754 AAH51884 BAA92063 BAB14989 BAC03881 BAF82795

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca