Version 5.4
Bos taurus Protein: MCPH1
Summary
InnateDB Protein IDBP-679780.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCPH1
Protein Name microcephalin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000031555
InnateDB Gene IDBG-628423 (MCPH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000132 establishment of mitotic spindle orientation
GO:0010468 regulation of gene expression
GO:0021987 cerebral cortex development
GO:0043549 regulation of kinase activity
GO:0046605 regulation of centrosome cycle
GO:0050727 regulation of inflammatory response
GO:0060348 bone development
GO:0060623 regulation of chromosome condensation
GO:0071539 protein localization to centrosome
GO:0097150 neuronal stem cell maintenance
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001357 BRCT domain
IPR011364 Breast cancer type 1 susceptibility protein (BRCA1)
IPR029504 Microcephalin, mammal
PFAM PF00533
PF12738
PF12258
PRINTS PR00493
PIRSF PIRSF001734
SMART SM00292
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MFA9
UniProt Splice Variant
Entrez Gene 100125236
UniGene Bt.11907
RefSeq NP_001096785
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC154381 DAAA02059816 DAAA02059817 DAAA02059818 DAAA02059819
GenPept AAI54382

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca