InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.37835

Summary

InnateDB Protein

IDBP-679831.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.37835

Protein Name

endonuclease VIII-like 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007661

InnateDB Gene

IDBG-628467 (BT.37835)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000405	bubble DNA binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003684	damaged DNA binding
GO:0003690	double-stranded DNA binding
GO:0003697	single-stranded DNA binding
GO:0003824	catalytic activity
GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0016798	hydrolase activity, acting on glycosyl bonds
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0016829	lyase activity
GO:0019104	DNA N-glycosylase activity
GO:0046872	metal ion binding

Biological Process

GO:0000737	DNA catabolic process, endonucleolytic
GO:0006281	DNA repair
GO:0006284	base-excision repair
GO:0006289	nucleotide-excision repair
GO:0006974	cellular response to DNA damage stimulus
GO:0008152	metabolic process

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000214 Zinc finger, DNA glycosylase/AP lyase-type
IPR001876 Zinc finger, RanBP2-type
IPR010666 Zinc finger, GRF-type
IPR010979 Ribosomal protein S13-like, H2TH
IPR012319 DNA glycosylase/AP lyase, catalytic domain
IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding

PFAM

PF00641
PF06839
PF01149
PF06831

PRINTS

PIRSF

SMART

SM00547
SM00898

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3MHN7