Version 5.4
Bos taurus Protein: TOMM20
Summary
InnateDB Protein IDBP-679841.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOMM20
Protein Name Mitochondrial import receptor subunit TOM20 homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000733
InnateDB Gene IDBG-628477 (TOMM20)
Protein Structure
UniProt Annotation
Function Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion outer membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO:0051082 unfolded protein binding
Biological Process
GO:0006605 protein targeting
GO:0006626 protein targeting to mitochondrion
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0071806 protein transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005741 mitochondrial outer membrane
GO:0005742 mitochondrial outer membrane translocase complex
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002056 Protein import receptor MAS20-related
IPR022422 Protein import receptor MAS20, metazoan
IPR023392 Mitochondrial outer membrane translocase complex, subunit Tom20 domain
PFAM PF02064
PRINTS PR00351
PR01989
PIRSF PIRSF037707
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6H7B1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 781575
UniGene Bt.88531
RefSeq NP_001092653
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146178
GenPept AAI46179

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca