InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC25A4

Summary

InnateDB Protein

IDBP-679906.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC25A4

Protein Name

ADP/ATP translocase 1

Synonyms

ANT1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017580

InnateDB Gene

IDBG-628540 (SLC25A4)

Protein Structure

UniProt Annotation

Function

Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane.

Subcellular Localization

Mitochondrion inner membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0008637	apoptotic mitochondrial changes
GO:0055085	transmembrane transport
GO:0060546	negative regulation of necroptotic process

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002030 Mitochondrial brown fat uncoupling protein
IPR002067 Mitochondrial carrier protein
IPR002113 Adenine nucleotide translocator 1
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain

PFAM

PF00153

PRINTS

PR00784
PR00926
PR00927

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P02722

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

282478

UniGene

RefSeq

NP_777083

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

M13783 M24102

GenPept

AAA30363 AAA30768