Version 5.4
Bos taurus Protein: ASAH1
Summary
InnateDB Protein IDBP-679995.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASAH1
Protein Name Acid ceramidase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000014960
InnateDB Gene IDBG-628630 (ASAH1)
Protein Structure
UniProt Annotation
Function Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. {ECO:0000250}.
Subcellular Localization Lysosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0017040 ceramidase activity
Biological Process
GO:0006629 lipid metabolic process
Cellular Component
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR016699 Acid ceramidase-like
IPR029055 Nucleophile aminohydrolases, N-terminal
IPR029132 Choloylglycine hydrolase/NAAA C-terminal
PFAM PF02275
PRINTS
PIRSF PIRSF017632
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q17QB3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510620
UniGene Bt.62845
RefSeq NP_001068927
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118455
GenPept AAI18456

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca