Version 5.4
Bos taurus Protein: FGG
Summary
InnateDB Protein IDBP-680333.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FGG
Protein Name fibrinogen gamma-B chain precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008877
InnateDB Gene IDBG-628944 (FGG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005198 structural molecule activity
GO:0030674 protein binding, bridging
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0007160 cell-matrix adhesion
GO:0007165 signal transduction
GO:0030168 platelet activation
GO:0034116 positive regulation of heterotypic cell-cell adhesion
GO:0043623 cellular protein complex assembly
GO:0045907 positive regulation of vasoconstriction
GO:0045921 positive regulation of exocytosis
GO:0050714 positive regulation of protein secretion
GO:0051258 protein polymerization
GO:0051592 response to calcium ion
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070527 platelet aggregation
GO:0090277 positive regulation of peptide hormone secretion
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000352 negative regulation of endothelial cell apoptotic process
Cellular Component
GO:0005577 fibrinogen complex
GO:0005615 extracellular space
GO:0005938 cell cortex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0031091 platelet alpha granule
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR012290 Fibrinogen, alpha/beta/gamma chain, coiled coil domain
PFAM PF00147
PF08702
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MGU7
UniProt Splice Variant
Entrez Gene 280792
UniGene Bt.108900
RefSeq NP_776336
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02044108
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca