Version 5.4
Bos taurus Protein: BCL2L11
Summary
InnateDB Protein IDBP-680357.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L11
Protein Name BCL2-like 11 (apoptosis facilitator)
Synonyms Bim;
Species Bos taurus
Ensembl Protein ENSBTAP00000046015
InnateDB Gene IDBG-628964 (BCL2L11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001776 leukocyte homeostasis
GO:0001782 B cell homeostasis
GO:0001783 B cell apoptotic process
GO:0001822 kidney development
GO:0002260 lymphocyte homeostasis
GO:0002262 myeloid cell homeostasis
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007160 cell-matrix adhesion
GO:0007283 spermatogenesis
GO:0008584 male gonad development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791 post-embryonic development
GO:0030879 mammary gland development
GO:0032464 positive regulation of protein homooligomerization
GO:0034976 response to endoplasmic reticulum stress
GO:0035148 tube formation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042981 regulation of apoptotic process
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043583 ear development
GO:0045787 positive regulation of cell cycle
GO:0046620 regulation of organ growth
GO:0048066 developmental pigmentation
GO:0048070 regulation of developmental pigmentation
GO:0048536 spleen development
GO:0048538 thymus development
GO:0048563 post-embryonic organ morphogenesis
GO:0060139 positive regulation of apoptotic process by virus
GO:0060154 cellular process regulating host cell cycle in response to virus
GO:0070242 thymocyte apoptotic process
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902263 apoptotic process involved in embryonic digit morphogenesis
GO:2000271 positive regulation of fibroblast apoptotic process
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005874 microtubule
GO:0019898 extrinsic component of membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0097140 BIM-BCL-xl complex
GO:0097141 BIM-BCL-2 complex
Protein Structure and Domains
PDB ID
InterPro IPR014771 Apoptosis, Bim N-terminal
IPR015040 Bcl-x interacting, BH3 domain
PFAM PF06773
PF08945
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2YDF0
UniProt Splice Variant
Entrez Gene 507390
UniGene Bt.51915
RefSeq NP_001068778
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110253 DAAA02030087
GenPept AAI10254

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca