Version 5.4
Bos taurus Protein: KRIT1
Summary
InnateDB Protein IDBP-680385.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRIT1
Protein Name krev interaction trapped protein 1
Synonyms CCM1;
Species Bos taurus
Ensembl Protein ENSBTAP00000003566
InnateDB Gene IDBG-628986 (KRIT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0008017 microtubule binding
GO:0032403 protein complex binding
Biological Process
GO:0001937 negative regulation of endothelial cell proliferation
GO:0010596 negative regulation of endothelial cell migration
GO:0016525 negative regulation of angiogenesis
GO:0032092 positive regulation of protein binding
GO:0045454 cell redox homeostasis
GO:2000114 regulation of establishment of cell polarity
GO:2000352 negative regulation of endothelial cell apoptotic process
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR000299 FERM domain
IPR002110 Ankyrin repeat
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR020683 Ankyrin repeat-containing domain
IPR029071 Ubiquitin-related domain
PFAM PF00023
PF13606
PF00373
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
SM00295
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A7Z069
UniProt Splice Variant
Entrez Gene 407996
UniGene Bt.17132
RefSeq NP_001001166
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC153267 DAAA02009761 DAAA02009762
GenPept AAI53268

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca