InnateDB Protein
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IDBP-680545.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TMEM231
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Protein Name
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Transmembrane protein 231
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000020510
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InnateDB Gene
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IDBG-629153 (TMEM231)
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Protein Structure
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Function |
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell projection, cilium membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR019306
Transmembrane protein 231
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PFAM |
PF10149
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A7MB75
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
511832
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UniGene |
Bt.58778
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RefSeq |
NP_001094548
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC151375
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GenPept |
AAI51376
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