Version 5.4
Bos taurus Protein: DLX5
Summary
InnateDB Protein IDBP-680800.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLX5
Protein Name distal-less homeobox 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024811
InnateDB Gene IDBG-629399 (DLX5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0071837 HMG box domain binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0001958 endochondral ossification
GO:0006355 regulation of transcription, DNA-templated
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0008283 cell proliferation
GO:0030326 embryonic limb morphogenesis
GO:0030509 BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0042472 inner ear morphogenesis
GO:0043583 ear development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 palate development
GO:0060166 olfactory pit development
GO:0060322 head development
GO:0060325 face morphogenesis
GO:0060349 bone morphogenesis
GO:0071773 cellular response to BMP stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000047 Helix-turn-helix motif
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
IPR022135 Distal-less-like homeobox protein, N-terminal domain
PFAM PF00046
PF12413
PRINTS PR00031
PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1RMR7
UniProt Splice Variant
Entrez Gene 507415
UniGene Bt.16059
RefSeq NP_001068781
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114749 DAAA02009827
GenPept AAI14750

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca