InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MPO

Summary

InnateDB Protein

IDBP-680812.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MPO

Protein Name

myeloperoxidase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016989

InnateDB Gene

IDBG-629390 (MPO)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004601	peroxidase activity
GO:0008201	heparin binding
GO:0020037	heme binding

Biological Process

GO:0001878	response to yeast
GO:0002149	hypochlorous acid biosynthetic process
GO:0002679	respiratory burst involved in defense response
GO:0006979	response to oxidative stress
GO:0019430	removal of superoxide radicals
GO:0034374	low-density lipoprotein particle remodeling
GO:0042744	hydrogen peroxide catabolic process
GO:0044130	negative regulation of growth of symbiont in host
GO:0050832	defense response to fungus
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0030141	secretory granule
GO:0042582	azurophil granule
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR010255 Haem peroxidase
IPR019791 Haem peroxidase, animal

PFAM

PF03098

PRINTS

PR00457

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A6QPT4

UniProt Splice Variant

Entrez Gene

511206

UniGene

Bt.23901

RefSeq

NP_001106769

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC149472

GenPept

AAI49473