InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NDUFA4

Summary

InnateDB Protein

IDBP-680939.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFA4

Protein Name

NADH dehydrogenase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000014801

InnateDB Gene

IDBG-629534 (NDUFA4)

Protein Structure

UniProt Annotation

Function

Cytochrome c oxidase (COX, complex IV) is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. Required for complex IV maintenance (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity
GO:0032403	protein complex binding

Biological Process

GO:0055114	oxidation-reduction process
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0005751	mitochondrial respiratory chain complex IV
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome
GO:0070469	respiratory chain

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q01321

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

327704

UniGene

RefSeq

NP_787014

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102882 X64897

GenPept

AAI02883 CAA46106