InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RAD51C

Summary

InnateDB Protein

IDBP-681010.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAD51C

Protein Name

RAD51 homolog C (S. cerevisiae)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020012

InnateDB Gene

IDBG-629569 (RAD51C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000400	four-way junction DNA binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity
GO:0008821	crossover junction endodeoxyribonuclease activity

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0000737	DNA catabolic process, endonucleolytic
GO:0006200	ATP catabolic process
GO:0006259	DNA metabolic process
GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0007066	female meiosis sister chromatid cohesion
GO:0007131	reciprocal meiotic recombination
GO:0007141	male meiosis I
GO:0007283	spermatogenesis
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle

Cellular Component

GO:0005634	nucleus
GO:0005657	replication fork
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex
GO:0033065	Rad51C-XRCC3 complex
GO:0048471	perinuclear region of cytoplasm
GO:0048476	Holliday junction resolvase complex

Protein Structure and Domains

PDB ID

InterPro

IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical
IPR013632 DNA recombination and repair protein Rad51, C-terminal
IPR014774 Circadian clock protein KaiC/DNA repair protein RadA
IPR016467 DNA recombination and repair protein, RecA-like
IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF08423
PF06745

PRINTS

PIRSF

PIRSF005856

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite