InnateDB Protein
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IDBP-681052.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GINS4
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Protein Name
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DNA replication complex GINS protein SLD5
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000022773
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InnateDB Gene
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IDBG-629643 (GINS4)
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Protein Structure
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Function |
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008591
GINS complex, subunit Sld5
IPR021151
GINS complex
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PFAM |
PF05916
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PRINTS |
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PIRSF |
PIRSF007764
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A2VE40
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
616799
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UniGene |
Bt.48705
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RefSeq |
NP_001075929
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC133560
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GenPept |
AAI33561
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