InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SEC11A

Summary

InnateDB Protein

IDBP-681079.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC11A

Protein Name

Signal peptidase complex catalytic subunit SEC11A

Synonyms

SPC18;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000014925

InnateDB Gene

IDBG-629667 (SEC11A)

Protein Structure

UniProt Annotation

Function

Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.

Subcellular Localization

Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006465	signal peptide processing
GO:0006508	proteolysis

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031090	organelle membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome