InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SGPL1

Summary

InnateDB Protein

IDBP-681221.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SGPL1

Protein Name

sphingosine-1-phosphate lyase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000044620

InnateDB Gene

IDBG-629798 (SGPL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0016829	lyase activity
GO:0016831	carboxy-lyase activity
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0001553	luteinization
GO:0001570	vasculogenesis
GO:0001822	kidney development
GO:0006631	fatty acid metabolic process
GO:0006672	ceramide metabolic process
GO:0006807	nitrogen compound metabolic process
GO:0007283	spermatogenesis
GO:0008152	metabolic process
GO:0008209	androgen metabolic process
GO:0008210	estrogen metabolic process
GO:0008585	female gonad development
GO:0009058	biosynthetic process
GO:0009791	post-embryonic development
GO:0010761	fibroblast migration
GO:0019752	carboxylic acid metabolic process
GO:0030097	hemopoiesis
GO:0033327	Leydig cell differentiation
GO:0040014	regulation of multicellular organism growth
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0048705	skeletal system morphogenesis
GO:0060021	palate development
GO:0060325	face morphogenesis
GO:0097194	execution phase of apoptosis

Cellular Component

GO:0005783

endoplasmic reticulum

Protein Structure and Domains

PDB ID

InterPro

IPR000192 Aminotransferase class V domain
IPR002129 Pyridoxal phosphate-dependent decarboxylase
IPR004839 Aminotransferase, class I/classII
IPR015424 Pyridoxal phosphate-dependent transferase

PFAM

PF00266
PF00282
PF00155

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-