Version 5.4
Bos taurus Protein: PPARD
Summary
InnateDB Protein IDBP-681290.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPARD
Protein Name peroxisome proliferator-activated receptor delta
Synonyms PPAR-beta;
Species Bos taurus
Ensembl Protein ENSBTAP00000023319
InnateDB Gene IDBG-629858 (PPARD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 protein binding
GO:0008144 drug binding
GO:0008270 zinc ion binding
GO:0008289 lipid binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0070539 linoleic acid binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001890 placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006629 lipid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0008283 cell proliferation
GO:0008284 positive regulation of cell proliferation
GO:0008366 axon ensheathment
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015908 fatty acid transport
GO:0030154 cell differentiation
GO:0031589 cell-substrate adhesion
GO:0042060 wound healing
GO:0042127 regulation of cell proliferation
GO:0042640 anagen
GO:0043401 steroid hormone mediated signaling pathway
GO:0043616 keratinocyte proliferation
GO:0045598 regulation of fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051546 keratinocyte migration
GO:0060612 adipose tissue development
GO:0071456 cellular response to hypoxia
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR003074 Peroxisome proliferator-activated receptor
IPR003075 Peroxisome proliferator-activated receptor, beta
IPR008946 Nuclear hormone receptor, ligand-binding
PFAM PF00104
PF00105
PRINTS PR00047
PR00398
PR01288
PR01290
PIRSF
SMART SM00430
SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A4IFL4
UniProt Splice Variant
Entrez Gene 353106
UniGene Bt.13264
RefSeq NP_001077105
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134636 DAAA02054950
GenPept AAI34637

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca