InnateDB Protein
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IDBP-681376.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ANAPC16
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Protein Name
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Anaphase-promoting complex subunit 16
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Synonyms
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APC16; C10orf104; C28H10orf104;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000000186
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InnateDB Gene
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IDBG-629950 (ANAPC16)
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Protein Structure
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Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
25 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q58DR0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
540089
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UniGene |
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RefSeq |
NP_001014960
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC114889
BT021537
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GenPept |
AAI14890
AAX46384
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