Bos taurus Protein: CLPS
Summary
InnateDB Protein IDBP-681414.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLPS
Protein Name Colipase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022391
InnateDB Gene IDBG-629985 (CLPS)
Protein Structure
UniProt Annotation
Function Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. {ECO:0000255PROSITE- ProRule:PRU00674}.Enterostatin has a biological activity as a satiety signal. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000255PROSITE- ProRule:PRU00674}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008047 enzyme activator activity
Biological Process
GO:0006629 lipid metabolic process
GO:0007586 digestion
GO:0016042 lipid catabolic process
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005576 extracellular region
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001981 Colipase
IPR017913 Colipase, N-terminal
IPR017914 Colipase, C-terminal
PFAM PF01114
PF02740
PRINTS PR00128
PIRSF
SMART SM00023
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A0JNQ7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 525923
UniGene
RefSeq NP_001071435
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126854 BC142041
GenPept AAI26855 AAI42042