Version 5.4
Bos taurus Protein: LIFR
Summary
InnateDB Protein IDBP-681463.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIFR
Protein Name leukemia inhibitory factor receptor alpha
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000013754
InnateDB Gene IDBG-630017 (LIFR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0004897 ciliary neurotrophic factor receptor activity
GO:0004923 leukemia inhibitory factor receptor activity
GO:0004924 oncostatin-M receptor activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005515 protein binding
GO:0019838 growth factor binding
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0034097 response to cytokine
GO:0038165 oncostatin-M-mediated signaling pathway
GO:0048861 leukemia inhibitory factor signaling pathway
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
PFAM PF00041
PF01108
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BAT3
UniProt Splice Variant
Entrez Gene 539504
UniGene Bt.52577
RefSeq NP_001179192
HUGO HGNC:6597
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050591
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca