Version 5.4
Bos taurus Protein: SDHC
Summary
InnateDB Protein IDBP-681555.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDHC
Protein Name Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021075
InnateDB Gene IDBG-630115 (SDHC)
Protein Structure
UniProt Annotation
Function Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular Localization Mitochondrion inner membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000104 succinate dehydrogenase activity
GO:0009055 electron carrier activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005749 mitochondrial respiratory chain complex II
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045281 succinate dehydrogenase complex
Protein Structure and Domains
PDB ID
InterPro IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit
IPR014314 Succinate dehydrogenase, cytochrome b556 subunit
IPR014361 Succinate dehydrogenase, cytochrome b560 subunit
PFAM PF01127
PRINTS
PIRSF PIRSF000178
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P35720
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 327696
UniGene
RefSeq NP_787008
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102062 BT025477 M76747 S74803
GenPept AAA21608 AAB32390 AAI02063 ABF57433

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca