InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FTSJD2

Summary

InnateDB Protein

IDBP-681787.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FTSJD2

Protein Name

Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

Synonyms

FTSJD2; MTr1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022726

InnateDB Gene

IDBG-630333 (FTSJD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
GO:0005515	protein binding
GO:0008168	methyltransferase activity
GO:0016740	transferase activity

Biological Process

GO:0006370	7-methylguanosine mRNA capping
GO:0006397	mRNA processing
GO:0032259	methylation
GO:0080009	mRNA methylation
GO:0097309	cap1 mRNA methylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000467 G-patch domain
IPR001202 WW domain
IPR002877 Ribosomal RNA methyltransferase FtsJ domain
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01585
PF00397
PF01728

PRINTS

PIRSF

SMART

SM00443
SM00456

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2VE39