InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CHRNA7

Summary

InnateDB Protein

IDBP-682307.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHRNA7

Protein Name

neuronal acetylcholine receptor subunit alpha-7 precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020942

InnateDB Gene

IDBG-630821 (CHRNA7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004889	acetylcholine-activated cation-selective channel activity
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005515	protein binding

Biological Process

GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
GO:0006810	transport
GO:0006811	ion transport
GO:0006897	endocytosis
GO:0007271	synaptic transmission, cholinergic
GO:0007613	memory
GO:0008306	associative learning
GO:0014061	regulation of norepinephrine secretion
GO:0030317	sperm motility
GO:0032094	response to food
GO:0032225	regulation of synaptic transmission, dopaminergic
GO:0032691	negative regulation of interleukin-1 beta production
GO:0032715	negative regulation of interleukin-6 production
GO:0032720	negative regulation of tumor necrosis factor production
GO:0034220	ion transmembrane transport
GO:0035094	response to nicotine
GO:0035095	behavioral response to nicotine
GO:0042110	T cell activation
GO:0042113	B cell activation
GO:0042391	regulation of membrane potential
GO:0042698	ovulation cycle
GO:0045471	response to ethanol
GO:0048149	behavioral response to ethanol
GO:0050727	regulation of inflammatory response
GO:0050728	negative regulation of inflammatory response
GO:0060112	generation of ovulation cycle rhythm

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding

PFAM

PF02932
PF02931

PRINTS

PR00252

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite