InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: IL1RL1

Summary

InnateDB Protein

IDBP-682333.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IL1RL1

Protein Name

interleukin 1 receptor-like 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000024715

InnateDB Gene

IDBG-630831 (IL1RL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002113	interleukin-33 binding
GO:0002114	interleukin-33 receptor activity
GO:0004908	interleukin-1 receptor activity
GO:0005515	protein binding

Biological Process

GO:0002826	negative regulation of T-helper 1 type immune response
GO:0007165	signal transduction
GO:0032689	negative regulation of interferon-gamma production
GO:0032754	positive regulation of interleukin-5 production
GO:0038172	interleukin-33-mediated signaling pathway
GO:0043032	positive regulation of macrophage activation
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050729	positive regulation of inflammatory response
GO:0090197	positive regulation of chemokine secretion

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR007110 Immunoglobulin-like domain

PFAM

PF01582
PF13676

PRINTS

PR01536

PIRSF

SMART

SM00255
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt