InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RFFL

Summary

InnateDB Protein

IDBP-682391.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RFFL

Protein Name

ring finger and FYVE-like domain containing 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018136

InnateDB Gene

IDBG-630885 (RFFL)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0002039	p53 binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019901	protein kinase binding
GO:0031625	ubiquitin protein ligase binding
GO:0046872	metal ion binding

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006886	intracellular protein transport
GO:0010762	regulation of fibroblast migration
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936	protein K48-linked ubiquitination
GO:1901797	negative regulation of signal transduction by p53 class mediator
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Cellular Component

GO:0002947	tumor necrosis factor receptor superfamily complex
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0016023	cytoplasmic membrane-bounded vesicle