InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.25483

Summary

InnateDB Protein

IDBP-682402.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.25483

Protein Name

DNA ligase 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000024875

InnateDB Gene

IDBG-630910 (BT.25483)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003909	DNA ligase activity
GO:0003910	DNA ligase (ATP) activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity

Biological Process

GO:0006260	DNA replication
GO:0006281	DNA repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0006310	DNA recombination
GO:0006974	cellular response to DNA damage stimulus
GO:0043504	mitochondrial DNA repair
GO:0045910	negative regulation of DNA recombination
GO:0051103	DNA ligation involved in DNA repair
GO:0071897	DNA biosynthetic process

Cellular Component

GO:0000794	condensed nuclear chromosome
GO:0000795	synaptonemal complex
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000977 DNA ligase, ATP-dependent
IPR001510 Zinc finger, PARP-type
IPR012308 DNA ligase, ATP-dependent, N-terminal
IPR012309 DNA ligase, ATP-dependent, C-terminal
IPR012310 DNA ligase, ATP-dependent, central
IPR012340 Nucleic acid-binding, OB-fold

PFAM

PF00645
PF04675
PF04679
PF01068

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-