InnateDB Protein
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IDBP-682501.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PSMD11
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Protein Name
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26S proteasome non-ATPase regulatory subunit 11
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000025152
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InnateDB Gene
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IDBG-631002 (PSMD11)
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Protein Structure
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Function |
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 91 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
91 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000717
Proteasome component (PCI) domain
IPR013143
PCI/PINT associated module
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PFAM |
PF01399
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PRINTS |
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PIRSF |
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SMART |
SM00088
SM00753
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TIGRFAMs |
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Modification |
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SwissProt |
Q2KI42
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
513461
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UniGene |
Bt.2394
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RefSeq |
NP_001039613
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC112777
BT029888
DAAA02048509
DAAA02048510
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GenPept |
AAI12778
ABM06138
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