InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: UBR2

Summary

InnateDB Protein

IDBP-682597.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UBR2

Protein Name

ubiquitin protein ligase E3 component n-recognin 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007833

InnateDB Gene

IDBG-631094 (UBR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0070728	leucine binding

Biological Process

GO:0006342	chromatin silencing
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007141	male meiosis I
GO:0007283	spermatogenesis
GO:0030163	protein catabolic process
GO:0032007	negative regulation of TOR signaling
GO:0033522	histone H2A ubiquitination
GO:0071233	cellular response to leucine

Cellular Component

GO:0000151	ubiquitin ligase complex
GO:0000785	chromatin
GO:0005634	nucleus
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003126 Zinc finger, N-recognin
IPR003769 Adaptor protein ClpS, core
IPR013993 Zinc finger, N-recognin, metazoa
IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like

PFAM

PF02207
PF02617

PRINTS

PIRSF

SMART

SM00396

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite