Version 5.4
Bos taurus Protein: PCAF
Summary
InnateDB Protein IDBP-682903.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCAF
Protein Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000994
InnateDB Gene IDBG-631313 (PCAF)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 138 interaction(s) predicted by orthology.
Predicted by orthology
Total 138 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003712 transcription cofactor activity
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0004468 lysine N-acetyltransferase activity
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0008134 transcription factor binding
GO:0016407 acetyltransferase activity
GO:0019901 protein kinase binding
GO:0032403 protein complex binding
GO:0042826 histone deacetylase binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0008285 negative regulation of cell proliferation
GO:0010835 regulation of protein ADP-ribosylation
GO:0016573 histone acetylation
GO:0018076 N-terminal peptidyl-lysine acetylation
GO:0018393 internal peptidyl-lysine acetylation
GO:0018394 peptidyl-lysine acetylation
GO:0032869 cellular response to insulin stimulus
GO:0043966 histone H3 acetylation
GO:0043970 histone H3-K9 acetylation
GO:0045722 positive regulation of gluconeogenesis
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
GO:0031672 A band
GO:0031674 I band
GO:0042641 actomyosin
Protein Structure and Domains
PDB ID
InterPro IPR000182 GNAT domain
IPR001487 Bromodomain
IPR009464 PCAF, N-terminal
IPR016181 Acyl-CoA N-acyltransferase
IPR016376 Histone acetylase PCAF
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PF00439
PF06466
PRINTS PR00503
PIRSF PIRSF003048
SMART SM00297
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6RXL4
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY486454 DAAA02001057
GenPept AAR27831

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca