Version 5.4
Bos taurus Protein: ADCY7
Summary
InnateDB Protein IDBP-683156.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADCY7
Protein Name adenylate cyclase type 7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008153
InnateDB Gene IDBG-631601 (ADCY7)
Protein Structure
UniProt Annotation
Function This is a membrane-bound, calcium-inhibitable adenylyl cyclase.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Found exclusively in the retinal pigment epithelium.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004016 adenylate cyclase activity
GO:0005524 ATP binding
GO:0016829 lyase activity
GO:0016849 phosphorus-oxygen lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006171 cAMP biosynthetic process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0035556 intracellular signal transduction
GO:0071361 cellular response to ethanol
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
IPR009398 Adenylate cyclase-like
IPR029787 Nucleotide cyclase
PFAM PF00211
PF06327
PRINTS
PIRSF
SMART SM00044
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q29450
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281603
UniGene Bt.1165
RefSeq NP_776655
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL Z49806
GenPept CAA89894

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca