Version 5.4
Bos taurus Protein: SELP
Summary
InnateDB Protein IDBP-683442.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SELP
Protein Name P-selectin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000044117
InnateDB Gene IDBG-631778 (SELP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001530 lipopolysaccharide binding
GO:0001948 glycoprotein binding
GO:0005515 protein binding
GO:0008201 heparin binding
GO:0030246 carbohydrate binding
GO:0033691 sialic acid binding
GO:0042806 fucose binding
GO:0048306 calcium-dependent protein binding
GO:0070492 oligosaccharide binding
Biological Process
GO:0002687 positive regulation of leukocyte migration
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007157 heterophilic cell-cell adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0010572 positive regulation of platelet activation
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0033623 regulation of integrin activation
GO:0050900 leukocyte migration
GO:0050901 leukocyte tethering or rolling
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0031092 platelet alpha granule membrane
Protein Structure and Domains
PDB ID
InterPro IPR000436 Sushi/SCR/CCP
IPR000742 Epidermal growth factor-like domain
IPR001304 C-type lectin
IPR002396 Selectin superfamily
IPR016187 C-type lectin fold
PFAM PF00084
PF00008
PF00059
PRINTS PR00343
PIRSF
SMART SM00032
SM00181
SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BK92
UniProt Splice Variant
Entrez Gene 281486
UniGene Bt.4342
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02042850
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca