InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PKLR

Summary

InnateDB Protein

IDBP-683659.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PKLR

Protein Name

pyruvate kinase isozymes R/L

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000044193

InnateDB Gene

IDBG-632071 (PKLR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0003824	catalytic activity
GO:0004743	pyruvate kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0030955	potassium ion binding

Biological Process

GO:0006096	glycolytic process
GO:0016310	phosphorylation
GO:0051707	response to other organism

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001697 Pyruvate kinase
IPR011037 Pyruvate kinase-like, insert domain
IPR015793 Pyruvate kinase, barrel
IPR015795 Pyruvate kinase, C-terminal
IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain

PFAM

PF00224
PF02887

PRINTS

PR01050

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite